A national listeria outbreak emanating from Colorado cantaloupes has resulted in 21 deaths, tying for the worst food-poisoning outbreak in the U.S. in 26 years.

For several weeks scientists and food-safety authorities have been concerned about listeria-tainted cantaloupes that came from Jensen Farms in Holly, Colo. (and the company’s packing facility in Granada, Colo.) A Sept. 10 shipment of the cantaloupes to multiple states has reportedly caused 21 deaths and 109 cases of sickness.