Sen. Marco Rubio (R-Fla.), a possible White House candidate in 2016, said Tuesday he could not support the Senate-passed bill addressing the “fiscal cliff” because it will hurt the economy.

“Rapid economic growth and spending reforms are the only way out of the real fiscal cliff our nation is facing. But rapid economic growth and job creation will be made more difficult under the deal reached here in Washington,” he said in a statement, in what could become a rallying cry for skeptical House conservatives.

Rubio said thousands of small businesses will be forced to fire employees because of the income tax increase on family income over $450,000, which could affect businesses filing as S corporations and limited-liability corporations.