Former president George W. Bush said on CNN’s “State of the Union” that he thought that if the 2016 presidential race came down to his brother Jeb against Hillary Clinton, Clinton would end up the loser.

Host Candy Crowley noted that Bush had often jokingly called Bill Clinton his “brother from another mother,” and wondered what that made Hillary Clinton. “My sister-in-law!” laughed Bush.

“Do you think that your brother could run against your ‘sister-in-law?’” asked Crowley.

“Yeah,” said Bush, suddenly serious. “And I think he’d beat her.”

“Do you?” asked Crowley.

“I do,” he responded.